About Us

NEURON-COMPUTER INTERFACE

This is new technology recently developed at HOF. We are able to isolate primary patient neurons in vast quantities, a surprising result since human neurons rarely divide and are very difficult to maintain in culture. Our new resource may be effective as cell treatments for neurological disease, and to model neurological disorders. In the San Francisco Bay Area this also creates an opportunity to interact effectively with companies interested in brain-computer interfaces, where we are responsible for the biological side of the interface while others work on the electronic sensors and computer software.

Our Story

HOF Therapeutics has unmatched skills in a defined area of biology involved with culturing a variety of human cell types and then assembling them back into complex tissues and organs using our cell assembly programming (CAP) methods. There are many applications for this technology. In the process of investigating various organ applications we found that neurons can be isolated from patients easily and placed back into manufactured CAP organs for implantation.

Biological Science Drives Computer Interface

Human cells cultured from a biopsy

Neurons selected for culturing

Neurons forming interconnections in culture

Bio Marker MAP2 stains our neurons

Neurons added to a CAP culture

Neurons seen to form interconnections

HOF Therapeutics is seeking partnership with companies developing the next generation of neural-computer interfaces. There are many possible interactions with medical research organizations, but our company specializes in specific commercial applications. We have developed unique and novel solutions not available elsewhere to apply to problems in developing effective therapies.

For this project we are the only group who offers:

Human neurons in high quantity that are patient specific by a minimally invasive procedure as a preliminary step to prepare patient
adjustments to cultures to optimize specific neuron types
work with our staff to mix sensor chips with living neurons and score responses
implantation of sensor chips accompanied by premade neuronal connections
sensor implants increase number of neurons rather than only damaging existing neurons
effective cell interactions with other cell types for CAP organ constructs